You can replicate large distribution lists between Microsoft Exchange Server computers. If you have had problems replicating distribution lists, you can increase both the time available for the replication to run and the number of threads available to the replication process. Both of these settings apply to intrasite replication and will increase the resources available for intrasite replication.
For example, if you have a 17,000 member distribution list that takes more than the default of 35 minutes to replicate, change the available time to 480 minutes, and then change the number of threads from the default of 50 to 200.
To increase the time available for replication to run, create the following DWORD registry key.
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\ MSExchangeDS\Parameters\Replication async thread check (minutes)
Start by setting the value to 480 minutes. You may need to adjust this value for best results, depending on the size of the distribution lists, connection speed between computers, processor speed, available memory, and other factors.
To increase the number of threads available to the replication process, change the value of the following registry key.
HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\ MSExchangeDS\Parameters\Max Threads (EXDS+NSP+DRA)
Start by setting the value to decimal 200. You may need to adjust this value for best results.